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Exploring the Stamets Stack: Microdosing Protocol

6 min

Find out how to use the popular Stamets Stack as your microdosing protocol, developed by renowned mycologist Paul Stamets.

In the realm of microdosing psychedelics, various protocols have emerged, each offering its unique approach to harnessing the potential benefits of sub-perceptual doses of psychedelic substances. One such protocol that has gained attention in recent years is the Stamets Stack, named after its proponent, mycologist and author Paul Stamets.

In this article, we'll delve into the intricacies of the Stamets Stack microdosing protocol, exploring its origins, components, potential benefits, and considerations for those interested in adopting this regimen.

red and white mushroom

Origins of the Stamets Stack

The Stamets Stack was popularized by Paul Stamets, a renowned mycologist known for his research on fungi and their medicinal properties. Stemming from his deep fascination with mushrooms and their potential benefits for human health, Stamets developed the Stack as a synergistic combination of three key components: psilocybin mushrooms, lion's mane mushrooms, and niacin (vitamin B3).

Components of the Stamets Stack

  1. Psilocybin Mushrooms: The primary psychedelic component of the Stack, psilocybin mushrooms, are known for their psychoactive properties and potential therapeutic effects. In microdosing, small, sub-perceptual doses of dried psilocybin mushrooms are typically consumed every few days, aiming to enhance mood, creativity, and cognitive function without inducing hallucinations or altered states of consciousness.
  2. Lion's Mane Mushrooms: Lion's mane mushrooms (Hericium erinaceus) are revered for their neuroprotective and cognitive-enhancing properties. Rich in compounds like hericenones and erinacines, lion's mane has been studied for its potential to support brain health, promote nerve growth factor (NGF) production, and improve cognitive function. In the Stamets Stack, lion's mane supplements are often included to complement the cognitive benefits of microdosing psychedelics.
  3. Niacin (Vitamin B3): Niacin, a form of vitamin B3, plays a crucial role in energy metabolism and cardiovascular health. In the context of the Stamets Stack, niacin serves a unique purpose as a "gatekeeper" or "catalyst" for the microdosing experience. By including niacin alongside psilocybin and lion's mane, Stamets hypothesizes that the vitamin B3 helps facilitate the conversion of psilocybin into its active form, psilocin, thereby enhancing the efficacy and duration of the microdosing effects.

Dosage and timing

Finding the optimal dosage and timing is crucial for maximizing the potential benefits of the Stamets Stack while minimizing the risk of adverse effects.

Since individual responses to psychedelics can vary widely, it's essential to start with conservative doses and gradually adjust based on personal experience and tolerance.

Here's a recommended dosage and timing regimen for the Stamets Stack:

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